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This study was designed to systematically investigate the cartilage-protective effects of AOD9604, both alone and in combination with HA, using a well-established collagenase-induced OA rabbit model

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Rare adverse effects specific to cyanocobalamin may include mild transient diarrhea, particularly with initial doses, and very rarely, allergic reactions in sensitive individuals

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Metabolic rate increases occur through multiple mechanisms including brown adipose tissue activation