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Nature Reviews Cardiology

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Ozempic is administered as a once-weekly subcutaneous injection , typically starting at a low dose (0.25 mg for at least 4 weeks) and gradually increasing to therapeutic doses of 0.5 mg, 1 mg, or 2 mg at intervals of at least 4 weeks, depending on individual response and tolerability

Specifically, the only RCT aiming to investigate the BW lowering efficacy of mazdutide in patients without T2D was limited to Chinese patients and referred to different cut offs for the definition of obesity (BMI 28 kg/m 2 ) 49

10.1152/ajpendo.00223.2012 11 FrosenJ

Sex difference in the safety and efficacy of bariatric procedures: a systematic review and meta-analysis