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Murray BE, Singh KV, Ross RP, Heath JD, Dunny GM, et al

It activates GLP-1, GIP, and Glucagon receptors simultaneously, potentially driving more significant effects on: Pathway Focus: GLP-1 + GIP + Glucagon Key Differences at a Glance Which is Most Effective in Research

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Compared to the crystal structure or simulation of PF-06372222, these residues (marked red in e g ) were exposed to solvent by 40100 2 in the simulation of compound 2 ( g , i )