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Supports fat loss and endurance

however, this endpoint serves more as a mechanistic clue than a direct clinical benefit (106)

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Specifically, tryptophan, a precursor of 5-HT, is metabolized by intestinal microbiota

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Importantly, the review also notes that individual responses to incretin-based therapies can vary substantially, and weight regain commonly occurs if treatment is discontinued, highlighting the chronic nature of obesity management