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Other approaches include small-molecule mimetics and lifestyle interventions, such as phenolic-rich diets, which may enhance endogenous neurotrophin production [245247]
Grassi M, Grassi G (2005) Mathematical modelling and controlled drug delivery: Matrix systems
Jett et al., PMID 15817669) and ipamorelin's preclinical and Phase 1 work (Raun et al., PMID 9849822
Liver insulin-like growth factor-1 mediates effects of low-intensity vibration on wound healing in diabetic mice
the form necessary for normal absorption in the small intestine (see Absorption section below)
These studies strongly support the suggestion that therapies which reduce hepatic DAG and acetyl-CoA contents by suppressing hepatic de novo lipogenesis might effectively treat hepatic insulin resistance in T2DM
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