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Importantly, ROS does not only play the role of the bad and ugly

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TMAO has also been shown to induce inflammatory markers in mice and in human aortic endothelial cells and vascular smooth muscle cells owing to activation of MAPK, extracellular signal kinase, and NF-B signaling cascade, along with promoting the recruitment of activated leukocytes to endothelial cells

Its chemical structure alteration, incorporating an acetyl group, enables it to traverse the blood-brain barrier, promoting brain health and energy production simultaneously

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Yaman M (2007) Distribution of trace metal concentrations in paired cancerous and non-cancerous human stomach tissues