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These medications, including popular brands like Ozempic and Wegovy, work by mimicking the action of a natural hormone in the body called glucagon-like peptide-1 (GLP-1)
Currently, two ongoing clinical trials are investigating the role of GLP-1 RAs in IBD management, that would lead to further knowledge: a French study (ID NCT05196958) evaluating the safety and efficacy of GLP-1 RAs in treatment of DM2 in overweight IBD patients (115), and an American study (ID NCT06774079) comparing the efficacy of GLP-1 RAs tirzepatide versus diet in CD patients (116)
Both collagen and glutathione support healthy aging, but they work differently
It also incorporates GLP-2, a hormone previously found to promote intestinal growth and hypothesized to influence gut barrier integrity, intestinal permeability, and inflammatory pathways
doi 10.1016/j.bioactmat.2023.09.014 92 LeeJJ