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Genet 153B , 610618 (2010)

Early redox imbalance mediates hydroperoxide-induced apoptosis in mitotic competent undifferentiated PC-12 cells

First, a massive dataset is compiled, containing information on the physical, chemical, and mechanical properties of various biomaterials (e.g., polymer composition, molecular weight, porosity, stiffness) alongside corresponding biological outcomes (e.g., drug release kinetics, cell viability, BBB permeability)

Torpor decreases cell death (apoptosis) (193) by up-regulation of anti-apoptotic proteins such as Bcl-XL in an organ-specific manner (194, 195), and the necrotic tissue injury seems to be minimal (196)

However, mitochondrial glutaminase, GLS2, instead of GLS1, has been shown to be required for ferroptosis, although both enzymes catalyze glutamine to glutamate (Gao et al., 2015b)

Numerous preclinical studies have also suggested that tocotrienols might be beneficial in the prevention of chronic diseases (12)