The emerging role of the Nrf2-Keap1 signaling pathway in cancer, Genes Dev
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The upregulation of genes such as Zif268 has been proposed as part of the underlying mechanism
For the phase III clinical program, a total of eight studies were initiated that investigated the efficacy and safety of tirzepatide in comparison to various other established antidiabetic medications in T2D either in monotherapy, combination with metformin as baseline therapy, or metformin and insulin glargine as a baseline
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