Topical GHK-Cu serums are widely available but they deliver a much lower concentration to the dermis than subcutaneous injection because the peptide does not readily cross intact skin
Esther Bodde , Cosmetic & Medical Physician (MD) Last updated: March 2026 References: Pickart et al
They are not medicines or drugs, have not been evaluated or approved by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease
Short cell-penetrating peptides: a model of interactions with gene promoter sites
Melting point: 268C 0.5 g (0.35 mmol) BPC157 was dissolved in 10 ml of methanol containing 42.6 mg (0.35 mmol) of tris-(hydroxymethyl)-aminomethane (TRIS), sterile filtered through a 0.2 filter and dried by evaporation of methanol in a vacuum at 40C to obtain 0.56 g of white solid
Systemic GHK-Cu administration can produce a metallic taste, particularly with sublingual formulations