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Lipotropic compounds interact with fat metabolism by either hastening the removal or decreasing the amount of fat in the liver

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249 Furthermore, 5-FU/cisplatininduced interferon responses upregulate ADAR1 via JAK/STAT, promoting A-to-I RNA editing that stabilizes SCD1 mRNA, reprograms lipid metabolism, activates Wnt/-catenin signaling, and sustains stemness and chemoresistance in gastric cancer

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