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Several phytochemicals, including berberine and other isoquinoline alkaloids, inhibit the assembly and activation of NLRP3, reducing mature pro-inflammatory cytokine release and mitigating neuroinflammation and neuronal loss in PD models ( Beyond immunomodulation, many plant phytoconstituents exert antioxidant and mitochondrial protective effects that are crucial in neurodegeneration

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W., Auld, J., Ozcan, F., Aslan, M

It is commonly explored in research related to cognitive function, neurobiology, and cellular signaling mechanisms

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