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Male C57BL/6 J mice (810 weeks, Charles River) were maintained at 2123 C and light-dark cycles (12:12 h schedule, lights on at 07:00)
equipped with 10-kDa MWCO regenerated cellulose membrane) was purchased from Merk (Darmstadt, Germany)
Elife 6:e23781
Anti-aging and longevity peptides Epithalon: Standard shelf life: 28-30 days refrigerated Maximum: 30-35 days Short peptide sequence, stable Thymosin Alpha-1: Standard shelf life: 28-30 days refrigerated Maximum: 45 days (pharmaceutical grade) Relatively stable peptide Semax and Selank: Standard shelf life: 28-30 days refrigerated Maximum: 30-35 days Short peptides, stable Sexual health peptides PT-141 (Bremelanotide): Standard shelf life: 28-30 days refrigerated Maximum: 45 days (pharmaceutical Vyleesi) Stable peptide Melanotan II: Standard shelf life: 28-30 days refrigerated Maximum: 35-40 days Relatively stable Copper peptides (GHK-Cu) GHK-Cu injectable: Standard shelf life: 28-30 days refrigerated Maximum: 30 days (copper can catalyze oxidation) More sensitive than other peptides due to copper ion Special note: Copper peptides may show visible degradation (color change to greenish/blue) if stored too long
Together, these mechanisms create persistent constipation that some people describe as their most disruptive side effect
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