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Journal of Nutritional Biochemistry, 24(3), 207213
Meta-analyses and trials in adults have consistently shown that GLP-1 RA therapy lowers body weight by 5%15% depending on agent and dose (17, 24)
Many compounds that looked effective in animals later failed human trials or revealed safety concerns
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The GLP-1s mimic the bodys hormonal pathways, amplifying signals the body already uses to communicate things like hunger and fullness
This effect is dose-dependent
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