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Sleep deprivation and circadian disruption have been associated with impaired glucose tolerance and altered appetite-regulating hormones

Tirzepatide was found to lower diastolic blood pressure by 15.6 mmHg and systolic blood pressure by 2.8 to 12.6 mmHg.There was an observed average rise in pulse rate ranging from 0.7 to 8.3 beats per minute [54, 78]

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(2022) 8:e08799

Summary Successful treatment of obesity requires a multidisciplinary approach and multimodal therapy including dietary and behavioral strategies