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10.1016/j.ejphar.2014.07.051 143 TenbrockL.WolfJ.BonevaS.SchlechtA.AgostiniH.WieghoferP.et al (2022)
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TMAO and Cardiovascular Risk Important Concern: Koeth et al
Traditional proteomics-based methods, such as N-terminomics 37,38,39 and proteomic identification of protease cleavage sites 40 , are well suited for global analyses of protease activity but can be low throughput and may lack the sensitivity to detect low-frequency, yet biologically perturbative, off-target cleavage events
Existing research suggests a bidirectional relationship between AKI and CKD, with AKI promoting CKD development, which, in turn, heightens susceptibility to AKI [141]