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Western blot analysis of thoracic aorta proteins showed that the classic aging markers P21 and P16 were significantly downregulated following FOXO4-DRI treatment, whereas the expression levels of the cell proliferation marker Ki-67 and Lamin B, a key protein involved in nuclear structural stability, were markedly upregulated (Figure 1A)

An early study[12] measured an average bioavailability of 79% and a recent study[13] found a range 63%89%

A random sample of this product tested by the Florida Department of Agriculture and Consumer Services found it to contain lead levels at 4.7 ppm

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