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In sum, it is worthy to note that lipid peroxidation (LPO) products such as 4-hydroxynonenal (4-HNE) and malondialdehyde (MDA) arise as secondary messengers of oxidative stress, which is often counterbalanced by the cellular antioxidant defense system [133]
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Samples and standards were serially diluted in assay buffer and tested for cAMP accumulation in CHO cells expressing human GLP-1R as described above
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