Because of lack of renal clearance, serum values rose to more than a hundredfold from 422 pmol/L on average to 54 000 pmol/L, with 67 000 pmol/L as highest value, without side-effects
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Despite promising research, it is important to exercise caution when considering the potential benefits of GLP-1 agonists beyond diabetes and obesity
Sundar IK, Chung S, Hwang JW, Arunachalam G, Cook S, Yao H, Mazur W, Kinnula VL, Fisher AB, Rahman I: Peroxiredoxin 6 differentially regulates acute and chronic cigarette smokemediated lung inflammatory response and injury
In a report published late last month in the medical journal The BMJ , a group of American and Chinese researchers raise potential safety concerns about GLP-1 drugs, indicating that higher doses of the drugs were linked to increased risks of experiencing symptoms consistent with stomach paralysis, including persistent nausea, vomiting and irregular bowel movements
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