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SURMOUNT-1 enrolled 2,539 adults with obesity or overweight
Sublingual delivery bypasses first-pass metabolism in the liver, which theoretically allows for decent bioavailability
First-line weight management methods include dietary and exercise changes, but your doctor may be able to prescribe an additional medication to support your goals
The theory is that theres a disruption to the circulation in your optic nerve
However, you should still monitor for any unexpected changes
This structural modification increases melanocortin receptor (MC1R, MC3R, MC4R) agonist activity but also introduces conformational instability in aqueous solution
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