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Plantarum (P29-57) [79] did not affect the POS-induced anxiety-like behavior in the EPM at P54-56 [80] and at P57-63 [79]

It was the first hormone-mimicking drug to be approved to treat type 2 diabetes

Larger Trials and Longer-Term Findings Furthermore, a larger RCT of 140 participants observed significant improvements on global symptomatology and general and negative symptoms of schizophrenia in the NAC supplementation (2 g/d

The other authors declare no competing interests

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Immunohistochemical staining Immunohistochemical staining was carried out on representative formalin-fixed, paraffin-embedded tissues using the Bond Polymer Refine Detection system (Leica Biosystems Newcastle Ltd., Newcastle, UK) according to the manufacturer's instructions, with minor modifications