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Following a 2-month washout period, the mean MDS-UPDRS motor scores in the off-medication state were 2.9 points higher in the placebo group, underscoring the potential benefits of lixisenatide in early PD [100]

Cell Mol Life Sci 74:15771603

Potential complications may include side effects like gastrointestinal upset, and with heavy drinking, more serious complications like pancreatitis and kidney issues

Current evidence is reassuring regarding GLP-1 receptor agonists and pancreatic cancer risk

Exogenous monounsaturated fatty acids promote a ferroptosis-resistant cell state

Starting during a weekend or less busy period allows patients to manage common gastrointestinal side effects such as nausea without work pressures