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Oxytocin depends, at least in part, on estrogen, so as estrogen levels fall in perimenopause, women can find themselves feeling less attached to others...and less willing to put up with their quirks, tendencies, and general BS
While true pharmacological tolerance to GLP-1 receptor agonists is not well-established, tachyphylaxis of the gastric emptying effect has been documented with GLP-1 receptor agonists
Dondelinger, Y
Approximately 10-15% of people in the United States suffer from irritable bowel syndrome (IBS), yet only 5-7% receive a diagnosis, according to the American College of Gastroenterology
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B12 shots are also good for busy or forgetful folks
