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The targeting of Prx5 to mitochondria is highly conserved among species (Van der Eecken et al., 2011), and it has been associated with the protection of mtDNA from oxidative attacks (Banmeyer et al., 2005)

It has been shown that when the particle size is smaller than a specific threshold, referred to as the critical size (Table 1) [92], changes in particle characteristics may occur

The dose-response analysis suggested that doses exceeding 1,000 mg per day were most effective