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Oral GLP-1s require strict fasting and timing protocols, while most injections are taken once weekly without food restrictions
Orally administered geniposide and its iridoid analogs exhibit antinociceptive effects in the formalin-induced tonic flinching response via activation of spinal GLP-1Rs, potentially targeting the same binding sites as exendin (939) and exenatide [33]
Stability data for compounded injectable GSH is limited, and use outside of licensed clinical supervision raises both safety and regulatory concerns
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