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Neurol ., 15 (11), 627643
Notably, activation of GLP-1R + neurons in the hypothalamus and brainstem reduces food intake and promotes weight loss
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On fatigue and bloating A two-month clinical trial of a three-strain probiotic on athletes found that daily supplementation led to significant improvements in self-rated markers of fatigue and bloating, attributed to the strains ability to strengthen gut barrier integrity, enhance microbial diversity, and increase short-chain fatty acid production.28 The three strains in question were Clostridium butyricum WB-STR-0006, Akkermansia muciniphila WB-STR-0001, and Bifidobacterium infantis , alongside 211mg of inulin
Many patients notice a mild energy dip when their dose is increased, but it's usually milder and shorter-lived than the initial adjustment
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