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GLP-1 Receptor Agonists (Semaglutide, Tirzepatide) A meta-analysis found GLP-1 receptor agonists carry a 3.55-fold increased risk of injection site reactions compared to controls
To be market-worthy, the drug needed to remain active 24 hours a day, remain physically stable for long periods of time and be as or more potent than native GLP-1
Assessment of lithium induced cardiotoxicity in rats and the potential effect of selenium: subchronic study
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identified 12 human gut bacterial genera able to convert LCA to 3-oxoLCA and isoLCA: Adlercreutzia, Bifidobacterium, Enter-ocloster, Clostridium, Collinsella, Eggerthella, Gordonibacter, Monoglobus, Peptoniphilus, Phocea, Raoultibacter, and Mediterraneibacter [26]
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