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However, significant challenges remain, including the synthesis of stable tripeptides with good tissue penetration, insufficient understanding of their mechanisms of action, the scarcity of studies in larger animal models and human trials, and the lack of direct head-to-head comparisons with larger peptides [75, 95]

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United States and Canadian Academy of Pathology, 2007

E.MutchD.et al (2011)

We found that glycine supplementation significantly increased the plasma concentration of glycine and enhanced the formation and urinary excretion of several acylglycines

Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamicpituitaryadrenal axis in severe depression