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The authors found that treatment with antioxidants accounted for nearly 60% of the difference between in DNA damage treatment and control groups after the scan [56]

The liberated p53 then transcription-independently activates the pro-apoptotic protein BAX, thereby triggering the execution phase of apoptosis

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Moreover, knockdown of HNF4 by RNA interference directly resulted in downregulation of the major methionine metabolic enzymes at both the protein expression level and the relative mRNA level (Fig

Obara et al., 2002)