In GD, the major autoantigen (thyroid-stimulating hormone (TSH)-antibody) is to the receptor for the TSH, which causes overproduction of thyroid hormones, resulting in symptoms such as irritability, rapid heartbeat, weight loss, poor tolerance of heat and bulging eyes (Graves orbitopathy) ( Reference Effraimidis and Wiersinga 4 , Reference Marcocci, Kahaly and Krassas 7 , Reference Brent 8 )
Vincents Hospital Sydney, Australia Reviewed by Raffaele Carraro, La Princesa University Hospital, Spain Laura Marroqui, Miguel Hernndez University of Elche, Spain Updates Copyright 2024 Corrao, Pollicino, Maggio, Torres and Argano
The peptide portion is stable, but the metal-peptide complex requires careful handling to maintain the copper association
Researchers may use intravenous infusion, defined timing, strict observation, and selected participants
95% CI, 0.75 to 1.32), whereas the use of GLP-1 analogues was linked to an increased risk (6.1 vs
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