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It phosphorylates upstream stimulatory factor 1 (USF1) and then upregulate fatty acid synthase (FASN), which promotes de novo lipogenesis (DNL) in liver and aggravates hepatic fat deposition

Practical Notes: Half-life: Short, so timing and placement matter

How Diverticulitis Develops in the Sigmoid Colon Anatomy and Function of the Sigmoid Colon How Diverticula Form and Can Lead to Diverticulitis Abnormal colonic motility (or movement), which may cause pressure, is believed to be a risk factor for developing diverticula

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