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1- Ice the injection site Before injecting with vitamin B12, apply ice to your thigh, hip, or groin- wherever you plan on inserting the needle

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Int J Mol Sci 24:12767

Separately, GHK-Cu has documented antioxidant and anti-inflammatory activity in the literature, including suppression of certain free-radical species and modulation of inflammatory chemoattraction of macrophages and mast cells

[5] That action has been primarily observed in the GI tract, but research has noted similar observations in muscle, neurological, and cardiovascular tissues

Laboratory Monitoring Guidelines Regular lab tests are key to checking if B12 injections are working