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The IDH3 isoform is involved in the TCA cycle where it oxidatively decarboxylates isocitrate to 2-oxoglutarate (-ketoglutarate)

1 Maintaining these levels is essential to keeping our bodies functioning as well as possible

TXNIP downregulates V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MafA), a transcription factor to drive insulin expression, and thus negatively regulates insulin expression 25

Promoting cellular health

Altered central and blood glutathione in Alzheimers disease and mild cognitive impairment

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