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The SELECT trial (Lincoff and colleagues) of semaglutide in overweight or obese adults with established cardiovascular disease but without diabetes found a 20% reduction in major heart events

This, in turn, enhances self-efficacy and long-term adherence to exercise and dietary interventions, creating a positive feedback loop that indirectly benefits reproductive outcomes

S.SeiwerthS.RogicD.KusecV.et al (2004)

For others, side effects such as nausea, vomiting and diarrhea force them to halt the medications, Dushay said